HDAC inhibition induces expression of scaffolding proteins critical for tumor progression in pediatric glioma: focus on EBP50 and IRSp53.
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DOI: 10.1093/neuonc/noz215
Abstract: BACKGROUND Diffuse midline glioma (DMG) is a pediatric malignancy with poor prognosis. Most children die less than one year after diagnosis. Recently, mutations in histone H3 have been identified and are believed to be oncogenic… read more here.
Keywords: glioma; dmg; treatment; ebp50 irsp53 ... See more keywords