Pharmacokinetic Interactions Between the Fixed‐Dose Combinations of Elvitegravir/Cobicistat/Tenofovir Disoproxil Fumarate/Emtricitabine and Elbasvir/Grazoprevir in Healthy Adult Participants
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DOI: 10.1002/cpdd.702
Abstract: Treatment of individuals coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) requires careful consideration of potential drug‐drug interactions. The pharmacokinetic interaction of the HCV fixed‐dose combination treatment of elbasvir/grazoprevir (EBR/GZR) when coadministered… read more here.
Keywords: cob tdf; tdf ftc; ebr gzr; evg cob ... See more keywords
Elbasvir/grazoprevir and sofosbuvir for hepatitis C virus genotype 3 infection with compensated cirrhosis: A randomized trial
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DOI: 10.1002/hep.29852
Abstract: Many direct‐acting antiviral regimens have reduced activity in people with hepatitis C virus (HCV) genotype (GT) 3 infection and cirrhosis. The C‐ISLE study assessed the efficacy and safety of elbasvir/grazoprevir (EBR/GZR) plus sofosbuvir (SOF) with… read more here.
Keywords: ebr gzr; rbv; treatment; cirrhosis ... See more keywords
Evaluation of Pharmacokinetic Drug Interactions of the Direct-Acting Antiviral Agents Elbasvir and Grazoprevir with Pitavastatin, Rosuvastatin, Pravastatin, and Atorvastatin in Healthy Adults
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DOI: 10.1007/s40261-020-00974-8
Abstract: Many people infected with hepatitis C virus have comorbidities, including hypercholesterolemia, that are treated with statins. In this study, we evaluated the drug–drug interaction potential of the hepatitis C virus inhibitors elbasvir (EBR) and grazoprevir… read more here.
Keywords: ebr gzr; gzr; atorvastatin; drug ... See more keywords
Elbasvir/grazoprevir for hepatitis C virus genotype 1b East-Asian patients receiving hemodialysis
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DOI: 10.1038/s41598-020-66182-8
Abstract: Data regarding the efficacy and tolerability of elbasvir/grazoprevir (EBR/GZR) for East-Asian hepatitis C virus genotype 1b (HCV GT1b) patients receiving hemodialysis were limited. We prospectively recruited 40 HCV GT1b hemodialysis patients who received EBR/GZR for… read more here.
Keywords: hemodialysis; ebr gzr; treatment; patients receiving ... See more keywords
Real‐world effectiveness of elbasvir/grazoprevir In HCV‐infected patients in the US veterans affairs healthcare system
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DOI: 10.1111/jvh.12937
Abstract: Elbasvir/grazoprevir (EBR/GZR) is an all‐oral direct‐acting antiviral agent (DAA) with high sustained virologic response (SVR) in clinical trials. This study's primary objective was to evaluate effectiveness of EBR/GZR among HCV‐infected patients in a real‐world clinical… read more here.
Keywords: real world; ebr gzr; hcv infected; elbasvir grazoprevir ... See more keywords
Efficacy of Elbasvir/Grazoprevir Therapy in HCV Genotype-1 with or without HIV Infection: Role of HCV Core Antigen Monitoring and Improvement of Liver Stiffness and Steatosis
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DOI: 10.3851/imp3370
Abstract: Background The combination of elbasvir and grazoprevir (EBR/GZR) has been approved for treating HCV infection. This study aimed to evaluate the efficacy of EBR/GZR in terms of sustained virological response (SVR) and improvement of liver… read more here.
Keywords: elbasvir grazoprevir; infection; hcv; ebr gzr ... See more keywords