Serologic Response to the Epstein-Barr Virus Peptidome and the Risk for Multiple Sclerosis.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2024.0272
Abstract: Importance It remains unclear why only a small proportion of individuals infected with the Epstein-Barr virus (EBV) develop multiple sclerosis (MS) and what the underlying mechanisms are. Objective To assess the serologic response to all… read more here.
Keywords: epstein barr; ebna; risk; response ... See more keywords
MS is rare in EBV-seronegative children with CNS inflammatory demyelination.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of neurology"
DOI: 10.1002/ana.26062
Abstract: Although Epstein-Barr virus (EBV) is hypothesized to be a prerequisite for multiple sclerosis (MS), up to 15% of children with a diagnosis of MS were reported to be EBV-seronegative. When re-evaluating 25 EBV-seronegative children out… read more here.
Keywords: ebv seronegative; ebv; rare ebv; children cns ... See more keywords
Multiplex assays reveal anti‐EBV antibody profile and its implication in detection and diagnosis of nasopharyngeal carcinoma
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Cancer"
DOI: 10.1002/ijc.35061
Abstract: Epstein–Barr virus (EBV) is detected in nearly 100% of nonkeratinizing nasopharyngeal carcinoma (NPC) and EBV‐based biomarkers are used for NPC screening in endemic regions. Immunoglobulin A (IgA) against EBV nuclear antigen 1 (EBNA1) and viral… read more here.
Keywords: antibody; ebv; ebv antibody; antibody profile ... See more keywords
Detection of anti‐EBV TCR CDR3s associated with better outcomes for EBV‐positive, Ugandan cases of Burkitt lymphoma
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Cancer"
DOI: 10.1002/ijc.35212
Abstract: Burkitt lymphoma (BL) has a tight association with Epstein–Barr virus (EBV), especially in sub‐Saharan Africa. While the relationship between BL and EBV is well documented, the relationship between the anti‐EBV adaptive immune response, particularly in… read more here.
Keywords: burkitt lymphoma; anti ebv; ebv; positive ugandan ... See more keywords
Oncogenic effects of exosomes in γ‐herpesvirus‐associated neoplasms
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28573
Abstract: Kaposi's sarcoma‐associated herpesvirus (KSHV) and Epstein–Barr virus (EBV) are herpesviruses associated with human malignancies. As exosomes can shuttle many herpesvirus‐associated biomolecules from host cells to recipient cells, the exosomal pathway is utilized by herpesviruses to… read more here.
Keywords: associated neoplasms; ebv; exosomes herpesvirus; herpesvirus associated ... See more keywords
A comprehensive single cell data analysis of lymphoblastoid cells reveals the role of super‐enhancers in maintaining EBV latency
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28362
Abstract: We probed the lifecycle of EBV on a cell-by-cell basis using single cell RNA sequencing (scRNA-seq) data from nine publicly available lymphoblastoid cell lines (LCL). While the majority of LCLs comprised cells containing EBV in… read more here.
Keywords: cell; ebv; expression; single cell ... See more keywords
Establishment and characterization of two Epstein–Barr virus‐positive gastric cancer cell lines with epitheliotropic M81 strain undergoing distinct viral and altered cellular expression profiles
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28387
Abstract: Epstein–Barr virus (EBV)‐associated gastric cancer (EBVaGC) is a distinct subtype of gastric cancer (GC) distinguished by the presence of the EBV genome and limited viral gene expression within malignant epithelial cells. EBV infection is generally… read more here.
Keywords: expression profiles; ebv; expression; gastric cancer ... See more keywords
Evaluation of host cellular responses to Epstein–Barr virus (EBV) in adult lung transplant patients with EBV‐associated diseases
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28724
Abstract: Epstein–Barr virus (EBV) reactivation is commonly observed in lung transplant recipients (LTRs). However, cellular immune responses to EBV in adult LTRs have not been well described. We aimed to study CD4/CD8 ratio, EBV‐specific T cells… read more here.
Keywords: dnaemia; ebv; ebv dnaemia; ebv adult ... See more keywords
Terminal Repeat Analysis of EBV Genomes.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6655-4_12
Abstract: Epstein-Barr virus (EBV) was the first human virus associated directly with human malignancies. During EBV infection of various host cells the double-stranded linear EBV DNA carried by the virions undergoes circularization. Since there are variable… read more here.
Keywords: ebv; terminal restriction; analysis; ebv genomes ... See more keywords
Encyclopedia of EBV-Encoded Lytic Genes: An Update.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-10-7230-7_18
Abstract: In addition to latent genes, lytic genes of EBV must also be of extreme significance since propagation of the virus can be achieved only through execution of lytic cycle. Research on EBV lytic genes may… read more here.
Keywords: ebv; ebv lytic; encoded lytic; encyclopedia ebv ... See more keywords
EBV in T-/NK-Cell Tumorigenesis.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-10-7230-7_21
Abstract: Epstein-Barr virus (EBV), which is associated with B-cell proliferative disorders, also transforms T- or natural killer (NK)-lineage cells and has been connected with various T- or NK (T/NK)-cell malignancies, such as extranodal NK/T-cell lymphoma-nasal type… read more here.
Keywords: ebv; ebv associated; cell tumorigenesis; ebv cell ... See more keywords