Molecular mechanisms of EBV-driven cell cycle progression and oncogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-018-0570-1
Abstract: The early stage of oncogenesis is linked to the disorder of the cell cycle. Abnormal gene expression often leads to cell cycle disorders, resulting in malignant transformation of human cells. Epstein–Barr virus (EBV) is associated… read more here.
Keywords: cell cycle; ebv driven; mechanisms ebv; molecular mechanisms ... See more keywords
Abstract 1038: Xenograft-associated B cell lymphoproliferative disease as a surrogate model to study Epstein-Barr virus (EBV) driven lymphoma of the elderly
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-1038
Abstract: Background: Patient-derived tumor xenografts (PDX) are powerful tools to study cancer biology, cancer genomics and developmental therapeutics. A common problem in the development of PDX models is proliferation of atypical lymphocytes at the implant site,… read more here.
Keywords: xabld; disease; study; ebv driven ... See more keywords
Abstract LB-089: Targeting transferrin receptor 1 (TfR1) with the ch128.1/IgG1 antibody inhibits Epstein-Barr virus (EBV) driven lymphoproliferative growth and lymphomagenesis in immunosuppressed mice bearing human B cells
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-lb-089
Abstract: Epstein-Barr virus (EBV) is a human herpesvirus that is associated with malignancies of both B lymphocyte and epithelial cell origin. EBV is associated with the development of approximately 1.5% of all cancers worldwide, including AIDS-related… read more here.
Keywords: igg1; antibody; ebv driven; ch128 igg1 ... See more keywords
EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Blood"
DOI: 10.1182/blood.2022016975
Abstract: The development of a second malignancy after diagnosis of childhood acute lymphoblastic leukemia (ALL) is a rare event. Certain second malignancies have been linked with specific elements of leukemia therapy, yet the etiology of most… read more here.
Keywords: neoplasms associated; lymphoid neoplasms; ebv driven; therapy ... See more keywords
How Does Epstein–Barr Virus Interact With Other Microbiomes in EBV-Driven Cancers?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.852066
Abstract: The commensal microbiome refers to a large spectrum of microorganisms which mainly consists of viruses and bacteria, as well as some other components such as protozoa and fungi. Epstein–Barr virus (EBV) is considered as a… read more here.
Keywords: epstein barr; driven cancers; commensal microbiome; ebv driven ... See more keywords
Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecules"
DOI: 10.3390/biom9090482
Abstract: The oncogenic gammaherpesvirus Epstein–Barr virus (EBV) immortalizes in vitro B lymphocytes into lymphoblastoid cell lines (LCLs), a model that gives the opportunity to explore the molecular mechanisms driving viral tumorigenesis. In this study, we addressed… read more here.
Keywords: immortalization; cell immortalization; preventing ebv; ebv driven ... See more keywords