Genomic variations in EBNA3C of EBV associate with posttransplant lymphoproliferative disorder.
Sign Up to like & getrecommendations! Published in 2020 at "JCI insight"
DOI: 10.1172/jci.insight.131644
Abstract: Epstein-Barr Virus (EBV) is a ubiquitous virus linked to a variety of lymphoid and epithelial malignancies. In solid organ and hematopoietic stem cell transplant recipients, EBV is causally associated with posttransplant lymphoproliferative disorder (PTLD), a… read more here.
Keywords: posttransplant lymphoproliferative; variations ebna3c; ebv genome; ptld ... See more keywords
The nuclear lamina binds the EBV genome during latency and regulates viral gene expression
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DOI: 10.1371/journal.ppat.1010400
Abstract: The Epstein Barr virus (EBV) infects almost 95% of the population worldwide. While typically asymptomatic, EBV latent infection is associated with several malignancies of epithelial and lymphoid origin in immunocompromised individuals. In latently infected cells,… read more here.
Keywords: ebv genome; latency; gene expression; nuclear lamina ... See more keywords
Characterization of a new CCCTC-binding factor binding site as a dual regulator of Epstein-Barr virus latent infection
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DOI: 10.1371/journal.ppat.1011078
Abstract: Distinct viral gene expression characterizes Epstein-Barr virus (EBV) infection in EBV-producing marmoset B-cell (B95-8) and EBV-associated gastric carcinoma (SNU719) cell lines. CCCTC-binding factor (CTCF) is a structural chromatin factor that coordinates chromatin interactions in the… read more here.
Keywords: s13 locus; epstein barr; factor; ebv genome ... See more keywords
Three-Dimensional Chromatin Structure of the EBV Genome: A Crucial Factor in Viral Infection
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DOI: 10.3390/v15051088
Abstract: Epstein–Barr Virus (EBV) is a human gamma-herpesvirus that is widespread worldwide. To this day, about 200,000 cancer cases per year are attributed to EBV infection. EBV is capable of infecting both B cells and epithelial… read more here.
Keywords: infection; three dimensional; structure ebv; chromatin structure ... See more keywords