Immune checkpoints in T cells during oncogenic γ‐herpesvirus infections
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27840
Abstract: Epstein–Barr virus (EBV) and Kaposi sarcoma‐associated herpesvirus (KSHV) are two persistent oncogenic γ‐herpesviruses with an exclusive tropism for humans. They cause cancers of lymphocyte, epithelial and endothelial cell origin, such as Burkitt's and Hodgkin's lymphoma,… read more here.
Keywords: checkpoints cells; immune checkpoints; ebv kshv; cells oncogenic ... See more keywords
Structures of Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Virology"
DOI: 10.1128/jvi.01194-24
Abstract: ABSTRACT Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) are classified into the gammaherpesvirus subfamily of Herpesviridae, which stands out from its alpha- and betaherpesvirus relatives due to the tumorigenicity of its members. Although structures… read more here.
Keywords: epstein barr; envelope; kaposi sarcoma; virus ... See more keywords
An Ancestral Retrovirus Envelope Protein Regulates Persistent Gammaherpesvirus Lifecycles
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.708404
Abstract: Human gammaherpesviruses Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV) persist as life-long infections alternating between latency and lytic replication. Human endogenous retroviruses (HERVs), via integration into the host genome, represent genetic remnants of ancient… read more here.
Keywords: ebv kshv; lytic activation; envelope protein; activation ... See more keywords
Molecular Mechanisms of Flavonoids against Tumor Gamma-Herpesviruses and Their Correlated Cancers—A Focus on EBV and KSHV Life Cycles and Carcinogenesis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010247
Abstract: Epstein–Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) are cancer-causing viruses that belong to human gamma-herpesviruses. They are DNA viruses known to establish lifelong infections in humans, with the ability to develop various types of… read more here.
Keywords: life cycles; gamma; gamma herpesviruses; ebv kshv ... See more keywords