MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23380
Abstract: Chemoresistance remains a major obstacle to the treatment of esophageal cancer (EC). Exosome-mediated transfer of long noncoding RNAs (lncRNAs) has recently been unveiled to correlate with the regulation of drug resistance in EC. This study… read more here.
Keywords: ec109 cells; ptx resistance; miat; resistance ... See more keywords
XPD inhibits cell growth and invasion and enhances chemosensitivity in esophageal squamous cell carcinoma by regulating the PI3K/AKT signaling pathway
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2020.4593
Abstract: Esophageal squamous cell carcinoma (ESCC) is a lethal disease due to its high aggressiveness. The aim of the present study was to investigate the role of xeroderma pigmentosum complementation group D (XPD) in the growth… read more here.
Keywords: xpd; invasion; ec9706 ec109; pi3k akt ... See more keywords