Effects of nucleases on cell-free extrachromosomal circular DNA.
Sign Up to like & getrecommendations! Published in 2022 at "JCI insight"
DOI: 10.1172/jci.insight.156070
Abstract: Cell-free extrachromosomal circular DNA (eccDNA) as a distinct topological form from linear DNA has recently gained increasing research interest, with possible clinical applications as a class of biomarkers. In this study, we aimed to explore… read more here.
Keywords: mice; free extrachromosomal; dna; dnase1l3 ... See more keywords
Identification and Characterization of Extrachromosomal Circular DNA in Plasma of Lung Adenocarcinoma Patients
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DOI: 10.2147/ijgm.s363425
Abstract: Background Chromosome is the basic framework for eukaryotic cells to store genetic information, but certain genes exist in circulation, such as extrachromosomal circular DNA (eccDNA). The unique genetic characteristics and structure of eccDNA provide a… read more here.
Keywords: lung adenocarcinoma; eccdna; lung; adenocarcinoma patients ... See more keywords
Extrachromosomal Circular DNA (eccDNA): From Chaos to Function
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.792555
Abstract: Extrachromosomal circular DNA (eccDNA) is a type of double-stranded circular DNA that is derived and free from chromosomes. It has a strong heterogeneity in sequence, length, and origin and has been identified in both normal… read more here.
Keywords: circular dna; eccdna chaos; eccdna; dna eccdna ... See more keywords
Skeletal Muscles of Sedentary and Physically Active Aged People Have Distinctive Genic Extrachromosomal Circular DNA Profiles
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032736
Abstract: To bring new extrachromosomal circular DNA (eccDNA) enrichment technologies closer to the clinic, specifically for screening, early diagnosis, and monitoring of diseases or lifestyle conditions, it is paramount to identify the differential pattern of the… read more here.
Keywords: physically active; eccdna; group; gene ... See more keywords