Identification of Alzheimer's disease-associated rare coding variants in the ECE2 gene.
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DOI: 10.1172/jci.insight.135119
Abstract: Accumulation of amyloid β protein (Aβ) due to increased generation and/or impaired degradation plays an important role in Alzheimer's disease (AD) pathogenesis. In this report, we describe the identification of rare coding mutations in the… read more here.
Keywords: alzheimer disease; rare coding; ece2; gene ... See more keywords