Enhanced phosphorylation of sphingosine and ceramide sustains the exuberant proliferation of endothelial progenitors in Kaposi sarcoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.2ma0817-312r
Abstract: Endothelial colony‐forming cells (ECFCs), a unique endothelial stem cell population, are highly increased in the blood of Kaposi sarcoma (KS) patients. KS‐derived ECFCs (KS‐ECFCs) are also endowed with increased proliferative and vasculogenic potential, thus suggesting… read more here.
Keywords: kaposi sarcoma; proliferation; sphingosine; s1p ... See more keywords
Isolation and characterization of endothelial colony‐forming cells from mononuclear cells of rat bone marrow
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.06.013
Abstract: ABSTRACT Transplantation of bone marrow‐derived endothelial progenitor cells (BM‐EPCs) has been used as a therapeutic strategy for vascular repair. However, it remains controversial whether BM‐EPCs exhibit clonal endothelial colony‐forming cell (ECFC) capacity, a characteristic of… read more here.
Keywords: colony; rat bone; bone; ecfcs ... See more keywords
KSHV infection of endothelial precursor cells with lymphatic characteristics as a novel model for translational Kaposi’s sarcoma studies
Sign Up to like & getrecommendations! Published in 2022 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1010753
Abstract: Kaposi’s sarcoma herpesvirus (KSHV) is the etiologic agent of Kaposi’s sarcoma (KS), a hyperplasia consisting of enlarged malformed vasculature and spindle-shaped cells, the main proliferative component of KS. While spindle cells express markers of lymphatic… read more here.
Keywords: lymphatic ecfcs; spindle cells; kshv; kaposi sarcoma ... See more keywords