Echinacoside protects dopaminergic neurons by inhibiting NLRP3/Caspase-1/IL-1β signaling pathway in MPTP-induced Parkinson’s disease model
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.08.015
Abstract: Persistent microglia-mediated neuroinflammation contributes to the progressive loss of dopaminergic (DA) neurons in Parkinson's disease (PD). Recently, NOD-like receptor protein 3 (NLRP3) inflammasome-mediated neuroinflammation is considered to influence the pathogenesis of PD profoundly. Promoting DA… read more here.
Keywords: mptp; model; ech; parkinson disease ... See more keywords
Modulation of physicochemical properties of magnetic agarose microspheres by hydrolysis-suppressive sequential crosslinking
Sign Up to like & getrecommendations! Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2021.127607
Abstract: Abstract Separation and purification of target proteins are essential for drug discovery and development. A magnetic separation has been exploited due to its high efficiency. Despite many studies on chemical crosslinking of a magnetic agarose… read more here.
Keywords: sequential crosslinking; crosslinked mam; ech; magnetic agarose ... See more keywords
Electrochemically mediated reduction of epichlorohydrin pollutant by Ni(I)(hexamethylcyclam) in aqueous media
Sign Up to like & getrecommendations! Published in 2017 at "Electrochimica Acta"
DOI: 10.1016/j.electacta.2017.02.147
Abstract: Abstract Epichlorohydrin (ECH) is a volatile organic compound and toxic to human health. Here we investigated clean mediated electrocatalytic dechlorination of ECH in aqueous solutions using electrogenerated [Nickel(I)(hexamethylcyclam)] + ([Ni(I)(hmc)] + ) at glassy carbon… read more here.
Keywords: hexamethylcyclam; epichlorohydrin; ech; dechlorination ... See more keywords
Ageing in extra-care housing: preparation, persistence and self-management at the boundary between the third and fourth age
Sign Up to like & getrecommendations! Published in 2019 at "Ageing and Society"
DOI: 10.1017/s0144686x19000849
Abstract: Abstract Extra-care housing (ECH) has been hailed as a potential solution to some of the problems associated with traditional forms of social care, since it allows older people to live independently, while also having access… read more here.
Keywords: care; extra care; ech; third fourth ... See more keywords
Functional Characterization of Structural Genomics Proteins in the Crotonase Superfamily.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00842
Abstract: Members of the Crotonase superfamily, a mechanistically diverse family of proteins that share a conserved quaternary structure, can often catalyze more than one reaction. However, the spectrum of activity for its members has not been… read more here.
Keywords: hydrolase activity; structural genomics; crotonase superfamily; genomics proteins ... See more keywords
Observation of the ECH effect on the impurity accumulation in the LHD
Sign Up to like & getrecommendations! Published in 2017 at "Physics of Plasmas"
DOI: 10.1063/1.4983626
Abstract: Recent experiments in the Large Helical Device (LHD) clearly show the ability of electron cyclotron heating (ECH) to control accumulation of impurities, as demonstrated by external injection of a tracer-encapsulated solid pellet (TESPEL). The impurity… read more here.
Keywords: ech; accumulation; impurity; lhd plasma ... See more keywords
Simulation study of electron cyclotron heating assisted start-up process in ITER
Sign Up to like & getrecommendations! Published in 2025 at "Physica Scripta"
DOI: 10.1088/1402-4896/ae20d2
Abstract: To ensure a robust tokamak start-up, electron cyclotron heating (ECH) assisted plasma initiation has been proposed. In this study, a zero-dimensional (0D) model studying tokamak start-up assisted by ECH has been redeveloped. To validate the… read more here.
Keywords: start; cyclotron heating; simulation; assisted start ... See more keywords
Evolution of ELMs, pedestal profiles and fluctuations in the inter-ELM period in NBI- and ECH-dominated discharges in DIII-D
Sign Up to like & getrecommendations! Published in 2021 at "Nuclear Fusion"
DOI: 10.1088/1741-4326/abe8b1
Abstract: In DIII-D, it has been observed that ELM frequency decreases by 40% and ELM spacing becomes more regular in time when heating is changed from pure neutral beam injection (NBI) to predominantly electron cyclotron heating… read more here.
Keywords: dominated discharges; frequency; pedestal profiles; ech ... See more keywords
Decoupling of peeling and ballooning thresholds for pedestal stability and reduction in ELM frequency via enhanced turbulence with edge electron cyclotron heating in DIII-D
Sign Up to like & getrecommendations! Published in 2024 at "Nuclear Fusion"
DOI: 10.1088/1741-4326/ad4d03
Abstract: The edge localized mode (ELM) frequency (f ELM) decreased by 63% when electron cyclotron heating (ECH) deposition location is shifted from ρ = 0.4 to ρ = 0.8 in DIII-D discharges where the power ratio… read more here.
Keywords: turbulence; elm frequency; ech; case ... See more keywords
Mutations in Ehrlichia chaffeensis Genes ECH_0660 and ECH_0665 Cause Transcriptional Changes in Response to Zinc or Iron Limitation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bacteriology"
DOI: 10.1128/jb.00027-21
Abstract: Ehrlichia chaffeensis, a tick-transmitted bacterium, causes human monocytic ehrlichiosis by replicating within phagosomes of monocytes/macrophages. A function disruption mutation within the pathogen’s gene encoding a phage head-to-tail connector protein resulted in the rapid clearance of… read more here.
Keywords: pathogen; chaffeensis; zinc iron; gene ... See more keywords
Beneficial Effects of Echinacoside on Diabetic Cardiomyopathy in Diabetic Db/Db Mice
Sign Up to like & getrecommendations! Published in 2020 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s276972
Abstract: Purpose In this study, we investigated the protective effects and mechanism of action of echinacoside (ECH) from cistanche tubulosa extract in cardiomyocytes of db/db diabetic mice. Methods Twenty healthy male db/db mice aged 8 weeks… read more here.
Keywords: ppar cpt; mice; lipid accumulation; diabetic mice ... See more keywords