Echinacoside protects dopaminergic neurons by inhibiting NLRP3/Caspase-1/IL-1β signaling pathway in MPTP-induced Parkinson’s disease model
Sign Up to like & getrecommendations! Published in 2020 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2020.08.015
Abstract: Persistent microglia-mediated neuroinflammation contributes to the progressive loss of dopaminergic (DA) neurons in Parkinson's disease (PD). Recently, NOD-like receptor protein 3 (NLRP3) inflammasome-mediated neuroinflammation is considered to influence the pathogenesis of PD profoundly. Promoting DA… read more here.
Keywords: mptp; model; ech; parkinson disease ... See more keywords
Modulation of physicochemical properties of magnetic agarose microspheres by hydrolysis-suppressive sequential crosslinking
Sign Up to like & getrecommendations! Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2021.127607
Abstract: Abstract Separation and purification of target proteins are essential for drug discovery and development. A magnetic separation has been exploited due to its high efficiency. Despite many studies on chemical crosslinking of a magnetic agarose… read more here.
Keywords: sequential crosslinking; crosslinked mam; ech; magnetic agarose ... See more keywords
Electrochemically mediated reduction of epichlorohydrin pollutant by Ni(I)(hexamethylcyclam) in aqueous media
Sign Up to like & getrecommendations! Published in 2017 at "Electrochimica Acta"
DOI: 10.1016/j.electacta.2017.02.147
Abstract: Abstract Epichlorohydrin (ECH) is a volatile organic compound and toxic to human health. Here we investigated clean mediated electrocatalytic dechlorination of ECH in aqueous solutions using electrogenerated [Nickel(I)(hexamethylcyclam)] + ([Ni(I)(hmc)] + ) at glassy carbon… read more here.
Keywords: hexamethylcyclam; epichlorohydrin; ech; dechlorination ... See more keywords
Ageing in extra-care housing: preparation, persistence and self-management at the boundary between the third and fourth age
Sign Up to like & getrecommendations! Published in 2019 at "Ageing and Society"
DOI: 10.1017/s0144686x19000849
Abstract: Abstract Extra-care housing (ECH) has been hailed as a potential solution to some of the problems associated with traditional forms of social care, since it allows older people to live independently, while also having access… read more here.
Keywords: care; extra care; ech; third fourth ... See more keywords
Functional Characterization of Structural Genomics Proteins in the Crotonase Superfamily.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00842
Abstract: Members of the Crotonase superfamily, a mechanistically diverse family of proteins that share a conserved quaternary structure, can often catalyze more than one reaction. However, the spectrum of activity for its members has not been… read more here.
Keywords: hydrolase activity; structural genomics; crotonase superfamily; genomics proteins ... See more keywords
Observation of the ECH effect on the impurity accumulation in the LHD
Sign Up to like & getrecommendations! Published in 2017 at "Physics of Plasmas"
DOI: 10.1063/1.4983626
Abstract: Recent experiments in the Large Helical Device (LHD) clearly show the ability of electron cyclotron heating (ECH) to control accumulation of impurities, as demonstrated by external injection of a tracer-encapsulated solid pellet (TESPEL). The impurity… read more here.
Keywords: ech; accumulation; impurity; lhd plasma ... See more keywords
Evolution of ELMs, pedestal profiles and fluctuations in the inter-ELM period in NBI- and ECH-dominated discharges in DIII-D
Sign Up to like & getrecommendations! Published in 2021 at "Nuclear Fusion"
DOI: 10.1088/1741-4326/abe8b1
Abstract: In DIII-D, it has been observed that ELM frequency decreases by 40% and ELM spacing becomes more regular in time when heating is changed from pure neutral beam injection (NBI) to predominantly electron cyclotron heating… read more here.
Keywords: dominated discharges; frequency; pedestal profiles; ech ... See more keywords
Mutations in Ehrlichia chaffeensis Genes ECH_0660 and ECH_0665 Cause Transcriptional Changes in Response to Zinc or Iron Limitation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bacteriology"
DOI: 10.1128/jb.00027-21
Abstract: Ehrlichia chaffeensis, a tick-transmitted bacterium, causes human monocytic ehrlichiosis by replicating within phagosomes of monocytes/macrophages. A function disruption mutation within the pathogen’s gene encoding a phage head-to-tail connector protein resulted in the rapid clearance of… read more here.
Keywords: pathogen; chaffeensis; zinc iron; gene ... See more keywords
Beneficial Effects of Echinacoside on Diabetic Cardiomyopathy in Diabetic Db/Db Mice
Sign Up to like & getrecommendations! Published in 2020 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s276972
Abstract: Purpose In this study, we investigated the protective effects and mechanism of action of echinacoside (ECH) from cistanche tubulosa extract in cardiomyocytes of db/db diabetic mice. Methods Twenty healthy male db/db mice aged 8 weeks… read more here.
Keywords: ppar cpt; mice; lipid accumulation; diabetic mice ... See more keywords
Exploration of the Effect and Potential Mechanism of Echinacoside Against Endometrial Cancer Based on Network Pharmacology and in vitro Experimental Verification
Sign Up to like & getrecommendations! Published in 2022 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s361955
Abstract: Background Endometrial cancer (EC) is one of the most common gynecological malignancies, especially in postmenopausal women. Echinacoside (ECH) is a major natural bioactive ingredient derived from Cistanches Herba and Echinacea that has a variety of… read more here.
Keywords: endometrial cancer; network; effect; pharmacology ... See more keywords
The Anti-Inflammatory Effect of Carrageenan/Echinochrom Complex at Experimental Endotoxemia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911702
Abstract: The anti-inflammatory effects of the CRG/Ech complex in LPS-induced endotoxemia were investigated in vivo in mice and in vitro in LPS-stimulated RAW 264.7 cells and peritoneal macrophages. The results indicated that the CRG/Ech complex suppressed… read more here.
Keywords: endotoxemia; ech; inflammatory effect; anti inflammatory ... See more keywords