The efficacy of an alternative mebendazole formulation in mice infected with Echinococcus multilocularis.
Sign Up to like & getrecommendations! Published in 2019 at "Acta tropica"
DOI: 10.1016/j.actatropica.2019.05.009
Abstract: This study was conducted to investigate the efficacy of a new formulation of MBZ oily suspension (MBZ-OS) in experimentally Echinococcus multilocularis-infected mice. MBZ-OS was prepared and administered to mice infected with E. multilocularis at 12.5… read more here.
Keywords: echinococcus multilocularis; mice infected; formulation; efficacy alternative ... See more keywords
Anti-echinococcal activity of menthol and a novel prodrug, menthol-pentanol, against Echinococcus multilocularis.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105411
Abstract: Alveolar echinococcosis is one of the most dangerous parasitic zoonoses. This disease, widely distributed in the northern hemisphere, is caused by the metacestode stage of the tapeworm Echinococcus multilocularis. All surgical and non-surgical patients should… read more here.
Keywords: menthol pentanol; echinococcus multilocularis; prodrug; menthol ... See more keywords
Enzymatic Characteristics and Preventive Effect of Leucine Aminopeptidase Against Echinococcus multilocularis.
Sign Up to like & getrecommendations! Published in 2021 at "Acta tropica"
DOI: 10.1016/j.actatropica.2021.106066
Abstract: Alveolar echinococcosis, a parasitic zoonotic disease caused by the larval stage of Echinococcus multilocularis infection, is a global epidemic in Eurasia and North America. Leucine aminopeptidase (LAP) of the M17 peptidase family could act on… read more here.
Keywords: lap; echinococcus multilocularis; rem lap; leucine aminopeptidase ... See more keywords
Optimized dexamethasone immunosuppression enables Echinococcus multilocularis liver establishment after oral egg inoculation in a rat model.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2017.02.003
Abstract: Comparable with immunocompetent humans, rats are considered highly resistant to Echinococcus multilocularis oncosphere invasion, both in nature and after experimental oral inoculation with eggs. Pharmacological immunosuppression with dexamethasone (DMX) was shown to abrogate the resistance… read more here.
Keywords: echinococcus multilocularis; inoculation; establishment; rcchan wist ... See more keywords
Repurposing of an old drug: In vitro and in vivo efficacies of buparvaquone against Echinococcus multilocularis
Sign Up to like & getrecommendations! Published in 2018 at "International Journal for Parasitology: Drugs and Drug Resistance"
DOI: 10.1016/j.ijpddr.2018.10.011
Abstract: The metacestode stage of the fox tapeworm Echinococcus multilocularis causes the lethal disease alveolar echinococcosis. Current chemotherapeutic treatment options are based on benzimidazoles (albendazole and mebendazole), which are insufficient and hence alternative drugs are needed.… read more here.
Keywords: echinococcus multilocularis; vivo; drug; multilocularis ... See more keywords
Echinococcus granulosussensu lato and Echinococcus multilocularis: A review.
Sign Up to like & getrecommendations! Published in 2020 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2020.11.010
Abstract: Echinococcus spp. have a global distribution and are found on every continent except Antarctica. Infections with these parasites are considered extremely serious, contributing to significant morbidity and mortality in addition to substantial economic losses to… read more here.
Keywords: echinococcus multilocularis; echinococcus; review; echinococcus granulosussensu ... See more keywords
Regulatory effects of Echinococcus multilocularis extracellular vesicles on RAW264.7 macrophages.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2017.01.012
Abstract: Extracellular vesicles (EVs) play a role in intercellular communications via exchanging biological molecules, being involved in host-parasite interplay. Little is to date known about E. multilocularis EVs and their biological activities. Here spherical EVs secreted… read more here.
Keywords: extracellular vesicles; regulatory effects; echinococcus multilocularis; effects echinococcus ... See more keywords
Echinococcus multilocularis genetic diversity in Swiss domestic pigs assessed by EmsB microsatellite analyzes.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary parasitology"
DOI: 10.1016/j.vetpar.2021.109429
Abstract: Assessing the genetic diversity of the parasite Echinococcus multilocularis provides key information about the temporal and spatial strain flow in a given area. Previous studies indicated that a historical endemic area conventionally presents a relatively… read more here.
Keywords: echinococcus multilocularis; diversity; genetic diversity; area ... See more keywords
The fox tapeworm, Echinococcus multilocularis, in grey wolves and dogs in Slovakia: epidemiology and genetic analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of helminthology"
DOI: 10.1017/s0022149x20000528
Abstract: Echinococcus multilocularis, the causative agent of human alveolar echinococcosis, is an important emerging parasite in the northern hemisphere. In epidemiological studies, the highest attention is being paid to foxes as the main reservoir hosts responsible… read more here.
Keywords: multilocularis grey; echinococcus multilocularis; dogs slovakia; wolves dogs ... See more keywords
Wind-borne dispersion of Echinococcus multilocularis eggs – a flight model
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Helminthology"
DOI: 10.1017/s0022149x22000360
Abstract: Abstract The alveolar hydatid disease, also known as alveolar echinococcosis, of humans is certainly one of the most dangerous zoonoses worldwide. The disease is caused by Echinococcus multilocularis – the fox tapeworm. Red foxes (Vulpes… read more here.
Keywords: wind borne; multilocularis; multilocularis eggs; model ... See more keywords
Echinococcus multilocularis in a Eurasian lynx (Lynx lynx) in Turkey
Sign Up to like & getrecommendations! Published in 2018 at "Parasitology"
DOI: 10.1017/s0031182018000082
Abstract: Abstract Echinococcus multilocularis is the causative agent of alveolar echinococcosis (AE), one of the most threatening zoonoses in Eurasia. Human AE is widespread in the Erzurum region of Turkey, but the situation of the disease… read more here.
Keywords: turkey; echinococcus multilocularis; lynx; lynx lynx ... See more keywords