Engineered Extracellular Matrices as Biomaterials of Tunable Composition and Function
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201605486
Abstract: Engineered and decellularized extracellular matrices (ECM) are receiving increasing interest in regenerative medicine as materials capable to induce cell growth/differentiation and tissue repair by physiological presentation of embedded cues. However, ECM production/decellularization processes and control… read more here.
Keywords: extracellular matrices; composition; ecm; cell ... See more keywords
Extracellular Matrix-Based Strategies for Immunomodulatory Biomaterials Engineering.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801578
Abstract: The extracellular matrix (ECM) is a complex and dynamic structural scaffold for cells within tissues and plays an important role in regulating cell function. Recently it has become appreciated that the ECM contains bioactive motifs… read more here.
Keywords: engineering; immunomodulatory biomaterials; matrix based; extracellular matrix ... See more keywords
Conducting Polymer‐ECM Scaffolds for Human Neuronal Cell Differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200941
Abstract: 3D cell culture formats more closely resemble tissue architecture complexity than 2D systems, which are lacking most of the cell–cell and cell–microenvironment interactions of the in vivo milieu. Scaffold‐based systems integrating natural biomaterials are extensively… read more here.
Keywords: cell; ecm; polymer ecm; ecm scaffolds ... See more keywords
MY-1 Loaded Nano-Hydroxyapatite Accelerated Bone Regeneration by Increasing Type III Collagen Deposition in Early-stage ECM via a Hsp47 Dependent Mechanism.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300332
Abstract: The extracellular matrix (ECM) plays a crucial part in regulating stem cell function through its distinctive mechanical and chemical effect. Therefore, it is worth studying how to activate the driving force of osteoblast cells by… read more here.
Keywords: regeneration; ecm; early stage; nano hydroxyapatite ... See more keywords
The Impact of the Cellular Environment and Aging on Modeling Alzheimer's Disease in 3D Cell Culture Models
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205037
Abstract: Creating a cellular model of Alzheimer's disease (AD) that accurately recapitulates disease pathology has been a longstanding challenge. Recent studies showed that human AD neural cells, integrated into three‐dimensional (3D) hydrogel matrix, display key features… read more here.
Keywords: ecm; disease; alzheimer disease; cellular environment ... See more keywords
A new strategy for the decellularization of whole organs by hydrostatic pressure
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Progress"
DOI: 10.1002/btpr.3248
Abstract: Tissue engineering has been able to develop novel decellularization‐recellularization techniques, which facilitates the research for the generation of functional organs. This is based in the initial obtention of the organ's extracellular matrix (ECM). Therefore, any… read more here.
Keywords: ecm; new strategy; hydrostatic pressure; decellularization ... See more keywords
The hepatic “matrisome” responds dynamically to injury: Characterization of transitional changes to the extracellular matrix in mice
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.28918
Abstract: The extracellular matrix (ECM) consists of diverse components that work bidirectionally with surrounding cells to create a responsive microenvironment. In some contexts (e.g., hepatic fibrosis), changes to the ECM are well recognized and understood. However,… read more here.
Keywords: extracellular matrix; hepatology; responds dynamically; ecm ... See more keywords
Chitosan-placental ECM composite thermos-responsive hydrogel as a biomimetic wound dressing with angiogenic property.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200386
Abstract: Attempts are being made to develop an ideal wound dressing with excellent biomechanical and biological properties. Here, a thermos-responsive hydrogel is fabricated using chitosan (CTS) with various concentrations (1%, 2.5%, and 5% w/v) of solubilized… read more here.
Keywords: ecm; thermos responsive; hydrogel; responsive hydrogel ... See more keywords
The mechanobiology of tendon fibroblasts under static and uniaxial cyclic load in a 3D tissue engineered model mimicking native extracellular matrix
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2975
Abstract: Tendon mechanobiology plays a vital role in tendon repair and regeneration; however, this mechanism is currently poorly understood. We tested the role of different mechanical loads on extracellular matrix (ECM) remodelling gene expression and the… read more here.
Keywords: tendon fibroblasts; extracellular matrix; tissue; tendon ... See more keywords
Functional Bioinformatics Analyses of the Matrisome and Integrin Adhesome.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0962-0_16
Abstract: The extracellular matrix (ECM) is the noncellular compartment of living organisms and is formed of a complex network of cross-linked proteins, which is collectively known as the matrisome. Apart from providing the structure for an… read more here.
Keywords: bioinformatics analyses; analyses matrisome; integrin adhesome; matrisome integrin ... See more keywords
Biomimetic Extracellular Matrices and Scaffolds Prepared from Cultured Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-0950-2_24
Abstract: Extracellular matrix (ECM) interacts with cells and provides important signals to control cell functions and to maintain homeostasis of living organisms. Composition of ECM in each tissue is dependent on cell type and cell phenotype.… read more here.
Keywords: cultured cells; ecm substrates; scaffolds prepared; substrates scaffolds ... See more keywords