Extracellular matrix (ECM) circulating peptide biomarkers as potential predictors of survival in patients (pts) with untreated metastatic pancreatic ductal adenocarcinoma (mPDA) receiving pegvorhyaluronidase alfa (PEGPH20), nab-paclitaxel (A), and gemcitabine (G).
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DOI: 10.1200/jco.2018.36.15_suppl.12030
Abstract: 12030Background: Hyaluronan (HA) and collagens are major constituents of the ECM. HA accumulation in the tumor microenvironment may result in elevated interstitial fluid pressure, vascular compress... read more here.
Keywords: biomarkers potential; circulating peptide; extracellular matrix; matrix ecm ... See more keywords