In situ sequestration of endogenous PDGF-BB with an ECM-mimetic sponge for accelerated wound healing.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.09.028
Abstract: Recapitulating the typical features of extracellular matrix (ECM) in engineered biomaterials is crucial for preparing a suitable niche to activate endogenous tissue repair. Here, we report the design and evaluation of an ECM-mimetic scaffold that… read more here.
Keywords: ecm mimetic; wound healing; endogenous pdgf; tissue ... See more keywords
Intelligent ECM mimetic injectable scaffolds based on functional collagen building blocks for tissue engineering and biomedical applications
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra02927f
Abstract: Hydrogels comprising natural extracellular matrix (ECM) components are very attractive as scaffolds for regenerative medicine applications due to their inherent biointeractive properties. Responsiv ... read more here.
Keywords: ecm mimetic; injectable scaffolds; intelligent ecm; mimetic injectable ... See more keywords
ECM-mimetic immunomodulatory hydrogel for methicillin-resistant Staphylococcus aureus–infected chronic skin wound healing
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn7006
Abstract: The treatment of difficult-to-heal wounds remains a substantial clinical challenge due to deteriorative tissue microenvironment including the loss of extracellular matrix (ECM), excessive inflammation, impaired angiogenesis, and bacterial infection. Inspired by the chemical components, fibrous… read more here.
Keywords: wound healing; ecm mimetic; hydrogel; methicillin resistant ... See more keywords