Abstract 2349: Investigating the effect of ECM stiffness on macrophage-derived exosome secretion and PDAC organoid progression
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2349
Abstract: Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate of only 11%. Current treatments that mostly target the cancer cells themselves, have not been able to significantly improve survival rates, meaning there is an urgent… read more here.
Keywords: ecm stiffness; derived exosome; exosome secretion; macrophage derived ... See more keywords
Effect of Extracellular Matrix Stiffness on Candesartan Efficacy in Anti-Fibrosis and Antioxidation
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DOI: 10.3390/antiox12030679
Abstract: Myocardial fibrosis progression and imbalanced redox state are closely associated with increased extracellular matrix (ECM) stiffness. Candesartan (CAN), an angiotensin II (Ang II) receptor inhibitor, has shown promising anti-fibrosis and antioxidant efficacy in previous cardiovascular… read more here.
Keywords: ecm stiffness; effect; stiffness; anti fibrosis ... See more keywords
Stiff Extracellular Matrix Promotes Invasive Behaviors of Trophoblast Cells
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DOI: 10.3390/bioengineering10030384
Abstract: The effect of extracellular matrix (ECM) stiffness on embryonic trophoblast cells invasion during mammalian embryo implantation remains largely unknown. In this study, we investigated the effects of ECM stiffness on various aspects of human trophoblast… read more here.
Keywords: ecm stiffness; stiff extracellular; extracellular matrix; trophoblast cells ... See more keywords