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   Articles with "ect2" as a keyword



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ECT2/PSMD14/PTTG1 axis promotes the proliferation of glioma through stabilizing E2F1

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recommendations! Published in 2019 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noy207

Abstract: BACKGROUND Epithelial cell transformation sequence 2 (ECT2) is upregulated in glioma and promotes glioma cell proliferation. A preliminary experiment showed a positive correlation between ECT2 and pituitary tumor-transforming gene 1 (PTTG1). The aim of this… read more here.

Keywords: glioma; psmd14; proliferation; ect2 ... See more keywords
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IDDF2019-ABS-0270 ECT2 Increases egfr expression and tumorigenicity by promoting Cdc42 activity in pancreatic cancer

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recommendations! Published in 2019 at "Gut"

DOI: 10.1136/gutjnl-2019-iddfabstracts.54

Abstract: Background The poor prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is partially attributed to the invasive and metastatic behavior of this disease. Epithelial cell transforming 2 (ECT2) is a guanine nucleotide exchange factor (GEF)… read more here.

Keywords: expression; cdc42; ect2; cell ... See more keywords
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miR-30a-5p Regulates Viability, Migration, and Invasion of Lung Adenocarcinoma Cells via Targeting ECT2

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recommendations! Published in 2021 at "Computational and Mathematical Methods in Medicine"

DOI: 10.1155/2021/6241469

Abstract: Objective The abnormal expression of epithelial cell transforming sequence 2 (ECT2) is often considered the driving factor for the growth and invasion of tumors. This study was performed to investigate the regulatory effect of miR-30a-5p… read more here.

Keywords: lung adenocarcinoma; invasion; ect2; expression ... See more keywords
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ECT2 Increases the stability of EGFR and Tumorigenicity by Inhibiting Grb2 Ubiquitination in Pancreatic Cancer

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recommendations! Published in 2020 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2020.589241

Abstract: The poor prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is associated with the invasion and metastasis of tumor cells. Epithelial cell transforming 2 (ECT2) is a guanine nucleotide exchange factor (GEF) of the Rho… read more here.

Keywords: ect2 increases; pancreatic cancer; ect2; increases stability ... See more keywords