LAUSR

Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse

Sign Up to like & get
recommendations!
2 Published in 2023 at "Science"

DOI: 10.1126/science.abp8933

Abstract: Cytotoxic T lymphocytes (CTLs) kill virus-infected and cancer cells through T cell receptor (TCR) recognition. How CTLs terminate signaling and disengage to allow serial killing has remained a mystery. TCR activation triggers membrane specialization within… read more here.

Keywords: immune synapse; ectocytosis; ectocytosis renders; signaling self ... See more keywords