Ectoine lozenges in the treatment of acute viral pharyngitis: a prospective, active-controlled clinical study
Sign Up to like & getrecommendations! Published in 2019 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-019-05324-9
Abstract: PurposeAcute pharyngitis is an uncomfortable disorder mostly caused by viruses and for which antibiotics are unwarranted. This study compared lozenges containing ectoine, a natural extremolyte, with hyaluronic acid lozenges and hypertonic saline gargle for symptomatic… read more here.
Keywords: ectoine; pharyngitis; hyaluronic acid; saline gargle ... See more keywords
Promoter engineering for high ectoine production in a lower saline medium by Halomonas hydrothermalis Y2.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology letters"
DOI: 10.1007/s10529-021-03084-3
Abstract: OBJECTIVES For the stress from fermenters, downstream processing equipment, and wastewater treatment to be alleviated, lowering salt-dependence in the ectoine synthesis process is of great significance in the moderately halotolerant Halomonas hydrothermalis Y2. RESULTS In… read more here.
Keywords: halomonas hydrothermalis; ectoine synthesis; lower saline; promoter ... See more keywords
High ectoine production by an engineered Halomonas hydrothermalis Y2 in a reduced salinity medium
Sign Up to like & getrecommendations! Published in 2019 at "Microbial Cell Factories"
DOI: 10.1186/s12934-019-1230-x
Abstract: BackgroundAs an attracted compatible solute, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid (ectoine) showed great potentials in various field. However, lower productivity and high saline medium seriously hinder its wide applications.ResultsThe entire ectoine metabolism, including pathways for ectoine synthesis and… read more here.
Keywords: production; medium; doea; salinity ... See more keywords
Adaptation to Varying Salinity in Halomonas elongata: Much More Than Ectoine Accumulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.846677
Abstract: The halophilic γ-proteobacterium Halomonas elongata DSM 2581T thrives at salt concentrations well above 10 % NaCl (1.7 M NaCl). A well-known osmoregulatory mechanism is the accumulation of the compatible solute ectoine within the cell in… read more here.
Keywords: adaptation; halomonas elongata; accumulation; ectoine accumulation ... See more keywords
Metabolic engineering of Halomonas elongata: Ectoine secretion is increased by demand and supply driven approaches
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.968983
Abstract: The application of naturally-derived biomolecules in everyday products, replacing conventional synthetic manufacturing, is an ever-increasing market. An example of this is the compatible solute ectoine, which is contained in a plethora of treatment formulations for… read more here.
Keywords: supply driven; halomonas elongata; demand; ectoine ... See more keywords
Exploring the Therapeutic Potential of Ectoine in Duchenne Muscular Dystrophy: Comparison with Taurine, a Supplement with Known Beneficial Effects in the mdx Mouse
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179567
Abstract: Duchenne Muscular Dystrophy (DMD) is a debilitating muscle disorder that condemns patients to year-long dependency on glucocorticoids. Chronic glucocorticoid use elicits many unfavourable side-effects without offering satisfying clinical improvement, thus, the search for alternative treatments… read more here.
Keywords: duchenne muscular; mdx mice; mdx mouse; ectoine ... See more keywords