Bariatric Surgery-Induced Resolution of Hypertension and Obstructive Sleep Apnea: Impact of Modulation of Body Fat, Ectopic Fat, Autonomic Nervous Activity, Inflammatory and Adipokine Profiles
Sign Up to like & getrecommendations! Published in 2017 at "Obesity Surgery"
DOI: 10.1007/s11695-017-2737-z
Abstract: BackgroundObesity-associated systemic hypertension (HTN) and obstructive sleep apnea (OSA) have multiple pathophysiological pathways including ectopic fat deposition, inflammation, altered adipokine profile, and increased sympathetic nervous activity. We characterized these potential mechanisms in severely obese patients… read more here.
Keywords: surgery; htn osa; ectopic fat; nervous activity ... See more keywords
Prostaglandin E2-EP4 Axis Promotes Lipolysis and Fibrosis in Adipose Tissue Leading to Ectopic Fat Deposition and Insulin Resistance.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108265
Abstract: Lipolysis, the breakdown of triglyceride storage in white adipose tissue, supplies fatty acids to other tissues as a fuel under fasting conditions. In morbid obesity, fibrosis limits adipocyte expandability, resulting in enforced lipolysis, ectopic fat… read more here.
Keywords: insulin; ectopic fat; lipolysis; adipose tissue ... See more keywords
Disulfide-bond A oxidoreductase-like protein protects against ectopic fat deposition and lipid-related kidney damage in diabetic nephropathy.
Sign Up to like & getrecommendations! Published in 2019 at "Kidney international"
DOI: 10.1016/j.kint.2018.10.038
Abstract: Ectopic fat deposition (EFD) in the kidney has been shown to play a causal role in diabetic nephropathy; however, the mechanism underlying EFD remains elusive. By transcriptome analysis, we found decreased expression levels of disulfide-bond… read more here.
Keywords: dsba; deposition; ectopic fat; diabetic nephropathy ... See more keywords
Quantitative assessment of abdominal ectopic fat deposits in patients with different glucose tolerance by using mDixon Quant MRI
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-92004-w
Abstract: This study aimed to quantitatively analyze the characteristics of abdominal ectopic fat deposition in patients with different glucose tolerance by using mDixon Quant MRI. A total of 98 patients and 38 healthy volunteers were included… read more here.
Keywords: ectopic fat; tolerance; glucose tolerance; abdominal ectopic ... See more keywords
Safety and efficacy of liraglutide on reducing visceral and ectopic fat in adults with or without type 2 diabetes mellitus: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.1111/dom.14908
Abstract: To assess the efficacy and safety of liraglutide to reduce visceral and ectopic fat in adults with or without type 2 diabetes mellitus (T2DM). read more here.
Keywords: adults without; ectopic fat; without type; type diabetes ... See more keywords
Behind BMI: The Potential Indicative Role of Abdominal Ectopic Fat on Glucose Metabolism
Sign Up to like & getrecommendations! Published in 2024 at "Obesity Facts"
DOI: 10.1159/000536160
Abstract: Introduction: The purpose of this study was to compare the difference in abdominal fat distribution between different metabolic groups and find the ectopic fat with the most risk significance. Methods: A total of 98 subjects… read more here.
Keywords: ectopic fat; glucose metabolism; metabolism; fat distribution ... See more keywords
Renal ectopic fat deposition and hemodynamics in type 2 diabetes mellitus assessment with magnetic resonance imaging
Sign Up to like & getrecommendations! Published in 2025 at "Insights into Imaging"
DOI: 10.1186/s13244-025-01971-1
Abstract: To assess renal perfusion and ectopic fat deposition in patients with type 2 diabetes mellitus (T2DM), and to evaluate the effects of ectopic fat deposition on renal hemodynamics. All participants underwent quantitative magnetic resonance imaging… read more here.
Keywords: fat deposition; renal ectopic; hemodynamics; ectopic fat ... See more keywords
Magnetic Resonance Imaging Assessment of Abdominal Ectopic Fat Deposition in Correlation With Cardiometabolic Risk Factors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.820023
Abstract: Purpose Ectopic fat accumulation and abdominal fat distribution may have different cardiometabolic risk profiles. This study aimed to assess the associations between various magnetic resonance imaging (MRI)-acquired fat depots and cardiometabolic risk factors. Methods A… read more here.
Keywords: area; ectopic fat; risk; risk factors ... See more keywords
The Causal Role of Ectopic Fat Deposition in the Pathogenesis of Metabolic Syndrome
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms252413238
Abstract: Consuming a “modern” Western diet and overnutrition may increase insulin secretion. Additionally, nutrition-mediated hyperinsulinemia is a major driver of ectopic fat deposition. The global prevalence of metabolic syndrome is high and growing. Within this context,… read more here.
Keywords: fat deposition; metabolic syndrome; ectopic fat; role ... See more keywords
Fatty Pancreas and Cardiometabolic Risk: Response of Ectopic Fat to Lifestyle and Surgical Interventions
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14224873
Abstract: Ectopic fat accumulation in non-adipose organs, such as the pancreas and liver, is associated with an increased risk of cardiometabolic disease. While clinical trials have focused on interventions to decrease body weight and liver fat,… read more here.
Keywords: ectopic fat; intervention; pancreatic fat; risk ... See more keywords
Ectopic fat deposition and its related abnormalities of lipid metabolism followed by nonalcoholic fatty pancreas
Sign Up to like & getrecommendations! Published in 2022 at "Endoscopic Ultrasound"
DOI: 10.4103/eus-d-21-00167
Abstract: Background and Objectives: The positive energy balance between caloric intake and caloric output increasing storage of triglycerides (TG) in adipocytes has made nonalcoholic fatty liver disease (NAFLD) one of the major public health problems in… read more here.
Keywords: nonalcoholic fatty; deposition related; ectopic fat; fat deposition ... See more keywords