Innate Immune Gene Transcript Level Associated with the Infection of Macrophages with Ectromelia Virus in Two Different Mouse Strains.
Sign Up to like & getrecommendations! Published in 2017 at "Viral immunology"
DOI: 10.1089/vim.2016.0173
Abstract: Poxviruses have evolved numerous mechanisms to avoid the immune response of the infected host, and many of these mechanisms have not been fully described. Here, we studied the transcriptional response of innate immune genes in… read more here.
Keywords: ectv mos; infection; mice; innate immune ... See more keywords
Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process
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DOI: 10.1186/s12866-019-1471-1
Abstract: BackgroundCathepsins are a group of endosomal proteases present in many cells including dendritic cells (DCs). The activity of cathepsins is regulated by their endogenous inhibitors – cystatins. Cathepsins are crucial to antigen processing during viral and… read more here.
Keywords: cathepsins cystatins; infection; cathepsin; dendritic cells ... See more keywords
The in Vitro Inhibitory Effect of Ectromelia Virus Infection on Innate and Adaptive Immune Properties of GM-CSF-Derived Bone Marrow Cells Is Mouse Strain-Independent
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.02539
Abstract: Ectromelia virus (ECTV) belongs to the Orthopoxvirus genus of the Poxviridae family and is a natural pathogen of mice. Certain strains of mice are highly susceptible to ECTV infection and develop mousepox, a lethal disease… read more here.
Keywords: adaptive immune; infection; immune response; innate adaptive ... See more keywords
Mitochondria-related gene expression profiles in murine fibroblasts and macrophages during later stages of ectromelia virus infection in vitro.
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DOI: 10.4149/av_2020_305
Abstract: Mitochondria are multitasking organelles that play a central role in energy production, survival and primary host defense against viral infections. Therefore, viruses target mitochondria dynamics and functions to benefit their replication and morphogenetic processes. We… read more here.
Keywords: infection; expression; mitochondria related; related genes ... See more keywords
Long actin-based cellular protrusions as novel evidence of the cytopathic effect induced in immune cells infected by the ectromelia virus
Sign Up to like & getrecommendations! Published in 2018 at "Central-European Journal of Immunology"
DOI: 10.5114/ceji.2018.81352
Abstract: The aim of the study was to evaluate the influence of ectromelia virus (ECTV) infection on actin cytoskeleton rearrangement in immune cells, such as macrophages and dendritic cells (DCs). Using scanning electron and fluorescence microscopy… read more here.
Keywords: actin based; based cellular; immune cells; long actin ... See more keywords