Effects of eculizumab treatment on quality of life in patients with paroxysmal nocturnal hemoglobinuria in Japan
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-2409-3
Abstract: In paroxysmal nocturnal hemoglobinuria (PNH), various symptoms due to intravascular hemolysis exert a negative impact on patients’ quality of life (QOL). To determine clinical factors related with improvements in QOL in PNH patients treated, we… read more here.
Keywords: eculizumab treatment; treatment; paroxysmal nocturnal; nocturnal hemoglobinuria ... See more keywords
COVID-19 and acute kidney injury in pediatric subjects: is there a place for eculizumab treatment?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Nephrology"
DOI: 10.1007/s40620-020-00859-1
Abstract: The coronavirus disease 2019 (COVID-19) pandemic is mostly affecting adult or elderly subjects often presenting with several co-morbidities [1]. The lack of children among the first cases described in Wuhan, China [2], and the mild… read more here.
Keywords: kidney injury; eculizumab treatment; treatment; disease ... See more keywords
Successful 7-Year Eculizumab Treatment of Plasmapheresis-Resistant Recurrent Atypical Hemolytic-Uremic Syndrome due to Complement Factor H Hybrid Gene: A Case Report.
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2018.02.012
Abstract: Atypical hemolytic-uremic syndrome (aHUS) is an extremely rare disease, and up to 70% of the patients have a genetic mutation in the encoding components of complement activation or anti-complement factor H autoantibodies. The risk of… read more here.
Keywords: eculizumab; eculizumab treatment; hybrid gene; complement factor ... See more keywords
Complement blockade with eculizumab for treatment of severe Coronavirus Disease 2019 in pregnancy: A case series
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Reproductive Immunology"
DOI: 10.1111/aji.13559
Abstract: We evaluated eculizumab, a complement protein C5 inhibitor, for treatment of severe COVID‐19 in pregnant and postpartum individuals. read more here.
Keywords: eculizumab treatment; complement; blockade eculizumab; complement blockade ... See more keywords
Eculizumab treatment and impaired opsonophagocytic killing of meningococci by whole blood from immunized adults.
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DOI: 10.1182/blood-2017-05-781450
Abstract: Eculizumab, a humanized anti-complement C5 monoclonal antibody (mAb) for treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome, blocks the terminal complement pathway required for serum bactericidal activity (SBA). Because treated patients are… read more here.
Keywords: eculizumab treatment; treatment impaired; treatment; blood ... See more keywords