Transition Metal and Photocatalyst Free Arylation via Photoexcitable Electron Donor Acceptor Complexes:Mediation and Catalysis
Sign Up to like & getrecommendations! Published in 2024 at "ChemCatChem"
DOI: 10.1002/cctc.202301526
Abstract: Visible‐light‐activated organic reactions unlock novel avenues for complex molecular transformations, impossible under standard “thermal” conditions, which makes them powerful tools in the arsenal of synthetic chemistry. However, transition metal‐based or organic photoredox catalysts are often… read more here.
Keywords: chemistry; transition metal; eda; electron donor ... See more keywords
Stability and bonding of carbon(0)‐iron−N2 complexes relevant to nitrogenase co‐factor: EDA‐NOCV analyses
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.27012
Abstract: The factors/structural features which are responsible for the binding, activation and reduction of N2 to NH3 by FeMoco of nitrogenase have not been completely understood well. Several relevant model complexes by Holland et al. and… read more here.
Keywords: bonding carbon; eda; eda nocv; nocv analyses ... See more keywords
ONIOM and FMO-EDA study of metabotropic glutamate receptor 1: Quantum insights into the allosteric binding site
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Quantum Chemistry"
DOI: 10.1002/qua.25617
Abstract: The crystal structure of metabotropic glutamate receptor 1 (mGluR1) complexed with 4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)thiazol-2-yl)-N-methylbenzamide (FITM, a negative allosteric modulator) and its twelve close structural analogs with a broad spectrum of affinities (2.4 nM 10 000 nM) were investigated… read more here.
Keywords: oniom fmo; fmo eda; metabotropic glutamate; glutamate receptor ... See more keywords
Progress, applications, and challenges in high-throughput effect-directed analysis for toxicity driver identification — is it time for HT-EDA?
Sign Up to like & getrecommendations! Published in 2024 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-024-05424-4
Abstract: The rapid increase in the production and global use of chemicals and their mixtures has raised concerns about their potential impact on human and environmental health. With advances in analytical techniques, in particular, high-resolution mass… read more here.
Keywords: high throughput; effect directed; directed analysis; eda ... See more keywords
Extra dimension algorithm: a breakthrough for optimization and enhancing DNN efficiency
Sign Up to like & getrecommendations! Published in 2024 at "Artificial Intelligence Review"
DOI: 10.1007/s10462-024-10991-0
Abstract: Proposing an efficient meta-heuristic to improve the inputs of a trainer in deep neural network (DNNs) is significant. According to the Kaluza’s theory, there exists an extra dimension in the universe. This paper proposes a… read more here.
Keywords: dimension algorithm; efficiency; extra dimension; eda ... See more keywords
Assessment of diets containing curcumin, epigallocatechin-3-gallate, docosahexaenoic acid and α-lipoic acid on amyloid load and inflammation in a male transgenic mouse model of Alzheimer's disease: Are combinations more effective?
Sign Up to like & getrecommendations! Published in 2019 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2018.11.026
Abstract: Increasingly, evidence is accumulating pointing at a protective role of a healthy diet at decreasing the risk of Alzheimer's disease. To test the effectiveness of nutritional components, the following food-derived compounds: curcumin alone (curcumin), curcumin… read more here.
Keywords: combination; alzheimer disease; load; eda ... See more keywords
Wearables Measuring Electrodermal Activity to Assess Perceived Stress in Care: A Scoping Review.
Sign Up to like & getrecommendations! Published in 2023 at "Acta neuropsychiatrica"
DOI: 10.1017/neu.2023.19
Abstract: BACKGROUND Chronic stress responses can lead to physical and behavioural health problems, often experienced and observed in the care of people with intellectual disabilities or people with dementia. Electrodermal activity (EDA) is a bio-signal for… read more here.
Keywords: stress; eda; perceived stress; care ... See more keywords
Solvent Anions Enable Photoinduced Borylation and Phosphonation of Aryl Halides via EDA Complexes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02631
Abstract: We report the synthesis of aryl boronic esters and aryl phosphonate esters promoted by visible-light in the absence of transition-metals or photoredox catalysts. The transformation proceeds at room temperature using sodium hydride, as a non-nucleophilic… read more here.
Keywords: enable photoinduced; aryl halides; eda; photoinduced borylation ... See more keywords
Visible-Light-Induced C-H Cyanoalkylation of Azauracils with Cycloketone Oxime Esters via Catalytic EDA Complex.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c00742
Abstract: Photoexcitation electron donor-acceptor (EDA) complexes provide an effective approach to produce radicals under mild conditions, while the catalytic version of EDA complex photoactivation remains scarce. Herein, we report a visible-light-induced organophotocatalytic pathway for the cyanoalkylation… read more here.
Keywords: cyanoalkylation azauracils; visible light; cyanoalkylation; eda ... See more keywords
Visible-Light-Mediated Metal/Base-Free Stereoselective C-Alkyl Glycosylation via EDA Complexes of Glycosyl Xanthates and NHC-Borane.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c00957
Abstract: Owing to the toxic reagent and high temperature required, the application of xanthate-based radical chemistry has been limited. To address these challenges, we report a metal- and base-free, photoinduced strategy for stereoselective C-alkyl glycosylation via… read more here.
Keywords: eda complexes; alkyl glycosylation; metal base; eda ... See more keywords
Photoinduced EDA Complexes Enabled C3 (Hetero)arylation of Indoles Using Amine as a Transient Occupying Group.
Sign Up to like & getrecommendations! Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c03052
Abstract: Herein, an EDA complex enabled selective C3 (hetero)arylation of indole was established, utilizing morpholine as the transient occupying group. This protocol is efficient, sustainable, and exhibits excellent substrate compatibility and functional group tolerance. Mechanistic studies… read more here.
Keywords: hetero arylation; group; eda; occupying group ... See more keywords