The tight junction protein cingulin regulates the vascular response to burn injury in a mouse model.
Sign Up to like & getrecommendations! Published in 2020 at "Microvascular research"
DOI: 10.1016/j.mvr.2020.104067
Abstract: Edema formation due to the collapse of physiological barriers and the associated delayed healing process is still a central problem in the treatment of burn injuries. In healthy individuals, tight junctions form a barrier to… read more here.
Keywords: burn injury; edema formation; cingulin; injury ... See more keywords
Impact of edema formation on functional outcome in pediatric stroke patients
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15576
Abstract: Quantitative lesion net water uptake (NWU) has been described as an imaging biomarker reflecting vasogenic edema as an early indicator of infarct progression. We hypothesized that edema formation measured by NWU is higher in children… read more here.
Keywords: impact edema; edema formation; formation functional; functional outcome ... See more keywords
Toward New AQP4 Inhibitors: ORI-TRN-002
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25020924
Abstract: Cerebral edema is a life-threatening condition that can cause permanent brain damage or death if left untreated. Existing therapies aim at mitigating the associated elevated intracranial pressure, yet they primarily alleviate pressure rather than prevent… read more here.
Keywords: trn 002; edema formation; aqp4 inhibitors; ori trn ... See more keywords