The helicase, DDX3X, interacts with poly(A)-binding protein 1 (PABP1) and caprin-1 at the leading edge of migrating fibroblasts and is required for efficient cell spreading
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DOI: 10.1042/bcj20170354
Abstract: DDX3X, a helicase, can interact directly with mRNA and translation initiation factors, regulating the selective translation of mRNAs that contain a structured 5′ untranslated region. This activity modulates the expression of mRNAs controlling cell cycle… read more here.
Keywords: protein; leading edge; ddx3x; edge migrating ... See more keywords