Into the multiverse of gene edited NK cell-based therapeutic strategies.
Sign Up to like & getrecommendations! Published in 2021 at "Cell stem cell"
DOI: 10.1016/j.stem.2021.11.004
Abstract: In this issue of Cell Stem Cell, Woan et al., (2021) investigate the anti-cancer activity of triple gene edited iPSC-derived natural killer (NK) cells and demonstrate that expression of a modified CD16a and interleukin (IL)-15 receptor… read more here.
Keywords: gene edited; cell based; multiverse gene; cell ... See more keywords
Regulatory Considerations for Genome-Edited T-cell Therapies.
Sign Up to like & getrecommendations! Published in 2024 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-24-0482
Abstract: Methods to engineer the genomes of human cells for therapeutic intervention continue to advance at a remarkable pace. Chimeric antigen receptor-engineered T lymphocytes have pioneered the way for these therapies, initially beginning with insertions of… read more here.
Keywords: regulatory considerations; genome edited; cell therapies; cell ... See more keywords