Gene editing based hearing impairment research and therapeutics
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.134326
Abstract: Hearing impairment affects 1 in 500 newborns worldwide and nearly one out of three people over the age of 65 (WHO, 2019). Hereditary hearing loss is the most common type of congenital deafness; genetic factors… read more here.
Keywords: impairment research; gene editing; hearing impairment; editing based ... See more keywords
Gene Editing-Based Technologies for Beta-hemoglobinopathies Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11060862
Abstract: Simple Summary β-thalassemia syndromes are clinically and genetically heterogeneous blood disorders presented by β-chain deficiency in hemoglobin production. Despite improvements in transfusion practices and chelation treatment, many lingering challenges have encouraged researchers to develop newer… read more here.
Keywords: editing based; gene editing; thalassemia; editing tools ... See more keywords
Toward the Development of Epigenome Editing-Based Therapeutics: Potentials and Challenges
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DOI: 10.3390/ijms24054778
Abstract: The advancement in epigenetics research over the past several decades has led to the potential application of epigenome-editing technologies for the treatment of various diseases. In particular, epigenome editing is potentially useful in the treatment… read more here.
Keywords: editing based; development epigenome; toward development; epigenome editing ... See more keywords