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Published in 2019 at "JACC: Basic to Translational Science"
DOI: 10.1016/j.jacbts.2018.11.004
Abstract: Summary A variety of genetic cardiovascular diseases may one day be curable using gene editing technology. Germline genome editing and correction promises to permanently remove monogenic cardiovascular disorders from the offspring and subsequent generations of…
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Keywords:
genome editing;
variety;
cardiovascular diseases;
editing cardiovascular ... See more keywords
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Published in 2017 at "Nature Reviews Cardiology"
DOI: 10.1038/nrcardio.2016.139
Abstract: Genome-editing tools, which include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9) systems, have emerged as an invaluable technology to achieve somatic and germline…
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Keywords:
cardiology;
genome editing;
editing cardiovascular;
cardiovascular diseases ... See more keywords