A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Cancer cell"
DOI: 10.1016/j.ccell.2018.03.026
Abstract: Adenosine (A) to inosine (I) RNA editing introduces many nucleotide changes in cancer transcriptomes. However, due to the complexity of post-transcriptional regulation, the contribution of RNA editing to proteomic diversity in human cancers remains unclear.… read more here.
Keywords: cancer; proteomic diversity; editing contributes; rna editing ... See more keywords
A-to-I RNA editing contributes to the persistence of predicted damaging mutations in populations
Sign Up to like & getrecommendations! Published in 2019 at "Genome Research"
DOI: 10.1101/gr.246033.118
Abstract: Adenosine-to-inosine (A-to-I) RNA editing is a very common co-/posttranscriptional modification that can lead to A-to-G changes at the RNA level and compensate for G-to-A genomic changes to a certain extent. It has been shown that… read more here.
Keywords: genomic changes; rna; nonsynonymous editing; editing contributes ... See more keywords