An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer
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DOI: 10.1093/nar/gkx667
Abstract: Abstract Adenosine-to-inosine (A-to-I) RNA editing, catalyzed by Adenosine DeAminases acting on double-stranded RNA(dsRNA) (ADAR), occurs predominantly in the 3′ untranslated regions (3′UTRs) of spliced mRNA. Here we uncover an unanticipated link between ADARs (ADAR1 and… read more here.
Keywords: editing dsrna; rna; rna editing; dsrna binding ... See more keywords