RNA Editing in Human and Mouse Tissues.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0787-9_10
Abstract: Adenosine-to-inosine (A-to-I) RNA editing is a fundamental posttranscriptional mechanism that greatly diversifies the transcriptome in many living organisms, including mammals. Multiple studies have demonstrated the importance of this process not just in normal development and… read more here.
Keywords: mouse tissues; human mouse; rna editing; editing human ... See more keywords
Precision editing in the human embryo
Sign Up to like & getrecommendations! Published in 2017 at "Nature Biotechnology"
DOI: 10.1038/nbt.3965
Abstract: volume 35 number 9 SePTember 2017 nature biotechnology A new study from Shoukhrat Mitalipov and collaborators in the United States, South Korea and China1 marks a major advance in genome editing of the human germline.… read more here.
Keywords: medicine; embryos; efficiency; cas9 ... See more keywords
Use of single guided Cas9 nickase to facilitate precise and efficient genome editing in human iPSCs
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89312-2
Abstract: Cas9 nucleases permit rapid and efficient generation of gene-edited cell lines. However, in typical protocols, mutations are intentionally introduced into the donor template to avoid the cleavage of donor template or re-cleavage of the successfully… read more here.
Keywords: guided cas9; genome editing; single guided; human ipscs ... See more keywords
Gene editing of human embryos is not contrary to human rights law: A reply to Drabiak.
Sign Up to like & getrecommendations! Published in 2021 at "Bioethics"
DOI: 10.1111/bioe.12945
Abstract: In an article in this journal, Katherine Drabiak argues that green lighting genome editing of human embryos is contrary to "fundamental human rights law." According to the author, genome editing of human embryos violates what… read more here.
Keywords: human embryos; gene editing; law; human rights ... See more keywords
Genome Editing of Human Embryo: Allow or Prohibit?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Advanced Research in Law and Economics"
DOI: 10.14505/jarle.v11.2(48).21
Abstract: Nowadays, the direction of both law-enforcement activity and dynamically developing statutory regulation is to involve genes and genetic constructions into civil-law transactions. However, the evaluation of such processes is complex within the scope of doctrine… read more here.
Keywords: genome editing; law; prohibit genome; human embryo ... See more keywords
Fast and Efficient Genome Editing of Human FOXP3+ Regulatory T Cells
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.655122
Abstract: FOXP3+ regulatory T cells (Tregs) are central for maintaining peripheral tolerance and immune homeostasis. Because of their immunosuppressive characteristics, Tregs are a potential therapeutic target in various diseases such as autoimmunity, transplantation and infectious diseases… read more here.
Keywords: human tregs; genome editing; editing human; foxp3 regulatory ... See more keywords