Therapeutic Gene Editing in Inherited Retinal Disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041292
Abstract: Since the development of CRISPR/Cas9 gene editing in 2012, therapeutic editing research has produced several phase 1-2a trials. Here we provide an overview of the mechanisms and applications of various gene-editing technologies including adeno-associated virus… read more here.
Keywords: editing inherited; gene editing; therapeutic gene; inherited retinal ... See more keywords
Commentary: CRISPR gene editing for inherited retinal dystrophies: Towards clinical translation
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_1010_22
Abstract: The clustered regularly interspaced short palindromic repeats (CRISPR) system won the Nobel Prize in 2020. What makes this technology intriguing is the ability of the CRISPR/ Cas9 effector molecules to identify and bind to specific… read more here.
Keywords: editing inherited; commentary crispr; crispr; gene editing ... See more keywords