Gene editing in liver diseases
Sign Up to like & getrecommendations! Published in 2024 at "FEBS Letters"
DOI: 10.1002/1873-3468.14989
Abstract: The deliberate and precise modification of the host genome using engineered nucleases represents a groundbreaking advancement in modern medicine. Several clinical trials employing these approaches to address metabolic liver disorders have been initiated, with recent… read more here.
Keywords: gene editing; liver diseases; medicine; gene ... See more keywords
A Versatile Nonviral Delivery System for Multiplex Gene-Editing in the Liver.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.202003537
Abstract: Recent advances in CRISPR present attractive genome-editing toolsets for therapeutic strategies at the genetic level. Here, a liposome-coated mesoporous silica nanoparticle (lipoMSN) is reported as an effective CRISPR delivery system for multiplex gene-editing in the… read more here.
Keywords: gene editing; multiplex gene; delivery system; editing liver ... See more keywords