The nucleotides they are a-changin': function of RNA binding proteins in post-transcriptional messenger RNA editing and modification in Arabidopsis.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in plant biology"
DOI: 10.1016/j.pbi.2018.05.010
Abstract: During and after transcription, the fate of an RNA molecule is almost entirely directed by the cohorts of interacting RNA-binding proteins (RBPs). RBPs regulate all stages of the life cycle of a messenger RNA (mRNA)… read more here.
Keywords: binding proteins; editing modification; rna; rna binding ... See more keywords
Prime Editing Modification with FEN1 Improves F508del Variant Editing in the CFTR Gene in Airway Basal Cells
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DOI: 10.3390/ijms26167943
Abstract: Prime editing is a promising approach for correcting pathogenic variants, but its efficiency remains variable across genomic contexts. Here, we systematically evaluated 12 modifications of the PEmax system for correcting the CFTR F508del pathogenic variant… read more here.
Keywords: fen1; basal cells; editing modification; prime editing ... See more keywords