Development of Base Editors for Simultaneously Editing Multiple Loci in Lactococcus lactis.
Sign Up to like & getrecommendations! Published in 2022 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00561
Abstract: Lactococcus lactis serves as the most extensively studied model organism and an important dairy species. Though CRISPR-Cas9 systems have been developed for robust genetic manipulations, simultaneously editing multiple endogenous loci in L. lactis is still… read more here.
Keywords: crispr; simultaneously editing; lactis; editing multiple ... See more keywords
Efficient base editing for multiple genes and loci in pigs using base editors
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10421-8
Abstract: Cytosine base editors (CBEs) enable programmable C-to-T conversion without DNA double-stranded breaks and homology-directed repair in a variety of organisms, which exhibit great potential for agricultural and biomedical applications. However, all reported cases only involved… read more here.
Keywords: base editing; multiple sites; efficient base; editing multiple ... See more keywords