In vivo base editing of post-mitotic sensory cells
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DOI: 10.1038/s41467-018-04580-3
Abstract: Programmable nucleases can introduce precise changes to genomic DNA through homology-directed repair (HDR). Unfortunately, HDR is largely restricted to mitotic cells, and is typically accompanied by an excess of stochastic insertions and deletions (indels). Here… read more here.
Keywords: base editing; editing post; post mitotic; base ... See more keywords