Articles with "editing system" as a keyword



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CoWebDraw: a real-time collaborative graphical editing system supporting multi-clients based on HTML5

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Published in 2017 at "Multimedia Tools and Applications"

DOI: 10.1007/s11042-017-5242-4

Abstract: Real-time collaborative graphical editing system allows a group of users simultaneously to view and edit the shared graphical documents from geographically dispersed sites connected by networks. The strategy of consistency maintenance is the key technique… read more here.

Keywords: time collaborative; system; real time; collaborative graphical ... See more keywords
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Utilization of the CRISPR-Cas9 Gene Editing System to Dissect Neuroinflammatory and Neuropharmacological Mechanisms in Parkinson’s Disease

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Published in 2019 at "Journal of Neuroimmune Pharmacology"

DOI: 10.1007/s11481-019-09844-3

Abstract: AbstractChronic and debilitating neurodegenerative diseases, such as Parkinson’s disease (PD), impose an immense medical, emotional, and economic burden on patients and society. Due to a complex interaction between genetic and environmental risk factors, the etiology… read more here.

Keywords: dissect neuroinflammatory; editing system; crispr; parkinson disease ... See more keywords
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Development of CRISPR-Cas9 genome editing system in Talaromyces marneffei.

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Published in 2021 at "Microbial pathogenesis"

DOI: 10.1016/j.micpath.2021.104822

Abstract: Talaromyces marneffei is an important pathogenic thermally dimorphic fungus causing systemic talaromycosis mainly prevalent in Southeast Asia. The dimorphic transition between mycelium and yeast is considered crucial for the pathogenicity of T. marneffei. However, the… read more here.

Keywords: system; crispr cas9; talaromyces marneffei; development crispr ... See more keywords
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Adenine Base Editing System for Pseudomonas and Prediction Workflow for Protein Dysfunction via ABE.

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Published in 2022 at "ACS synthetic biology"

DOI: 10.1021/acssynbio.2c00066

Abstract: Pseudomonas is a large genus that inhabits diverse environments due to its distinct metabolic versatility. Its applications range from environmental to industrial biotechnology. Molecular tools that allow precise and efficient genetic manipulation are required to… read more here.

Keywords: system; adenine base; dysfunction; prediction ... See more keywords
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Efficient generation of mouse models with the prime editing system

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Published in 2020 at "Cell Discovery"

DOI: 10.1038/s41421-020-0165-z

Abstract: Dear Editor, Most genetic diseases in humans are caused by singlenucleotide mutations. Although genome editing with either the CRISPR-based cytosine base editor (CBE) or the adenine base editor (ABE) holds great promise for gene correction… read more here.

Keywords: system; base; prime editing; efficiency ... See more keywords
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Modification of tomato breeding traits and plant hormone signaling by Target-AID, the genome-editing system inducing efficient nucleotide substitution

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Published in 2022 at "Horticulture Research"

DOI: 10.1093/hr/uhab004

Abstract: Abstract Target activation-induced cytidine deaminase (Target-AID), a novel CRISPR/Cas9-based genome-editing tool, confers the base-editing capability on the Cas9 genome-editing system. It involves the fusion of cytidine deaminase (CDA), which catalyzes cytidine (C) to uridine (U)… read more here.

Keywords: system; genome editing; target aid; target ... See more keywords
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An efficient CRISPR/Cas9‐based genome editing system for alkaliphilic Bacillus sp. N16‐5 and application in engineering xylose utilization for d‐lactic acid production

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Published in 2022 at "Microbial Biotechnology"

DOI: 10.1111/1751-7915.14131

Abstract: Alkaliphiles are considered more suitable chassis than traditional neutrophiles due to their excellent resistance to microbial contamination. Alkaliphilic Bacillus sp. N16‐5, an industrially interesting strain with great potential for the production of lactic acid and… read more here.

Keywords: genome editing; system; bacillus; alkaliphilic bacillus ... See more keywords
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A MAD7‐based genome editing system for Escherichia coli

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Published in 2023 at "Microbial Biotechnology"

DOI: 10.1111/1751-7915.14234

Abstract: A broad variety of biomolecules is industrially produced in bacteria and yeasts. These microbial expression hosts can be optimized through genetic engineering using CRISPR tools. Here, we designed and characterized such a modular genome editing… read more here.

Keywords: genome editing; system; escherichia coli; editing system ... See more keywords
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Establishment of an Efficient Genome Editing System in Lettuce Without Sacrificing Specificity

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Published in 2022 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2022.930592

Abstract: The efficiency of the CRISPR/Cas9 genome editing system remains limited in many crops. Utilizing strong promoters to boost the expression level of Cas9 are commonly used to improve the editing efficiency. However, these strategies also… read more here.

Keywords: genome editing; editing efficiency; cas9; editing system ... See more keywords
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Establishment of CRISPR/Cas9 Genome-Editing System Based on Dual sgRNAs in Flammulina filiformis

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Published in 2022 at "Journal of Fungi"

DOI: 10.3390/jof8070693

Abstract: Flammulina filiformis, previously known as Asian Flammulina velutipes, is one of the most commercially important edible fungi, with nutritional value and medicinal properties worldwide. However, precision genome editing using CRISPR/Cas9, which is a revolutionary technology… read more here.

Keywords: genome editing; crispr cas9; dual sgrnas; cas9 genome ... See more keywords