Articles with "editing toolkit" as a keyword



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Expanding C–T base editing toolkit with diversified cytidine deaminases

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Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-11562-6

Abstract: Base editing tools for cytosine to thymine (C–T) conversion enable genome manipulation at single base-pair resolution with high efficiency. Available base editors (BEs) for C–T conversion (CBEs) have restricted editing scopes and nonnegligible off-target effects,… read more here.

Keywords: base editing; editing toolkit; base editors; base ... See more keywords