CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells
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DOI: 10.1038/s41587-020-0609-x
Abstract: CRISPR-guided DNA cytosine and adenine base editors are widely used for many applications 1 – 4 but primarily create DNA base transitions (that is, pyrimidine-to-pyrimidine or purine-to-purine). Here we describe the engineering of two base… read more here.
Keywords: editors inducing; inducing targeted; base editors; crispr base ... See more keywords