Articles with "edn1" as a keyword



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The endothelin 1 and endothelin receptor A gene polymorphisms increase the risk of developing papillary thyroid cancer

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Published in 2018 at "Molecular Biology Reports"

DOI: 10.1007/s11033-018-4461-8

Abstract: The endothelin (EDN) axis (EDN1 and EDN1 receptor A, EDNRA) is involved in cellular growth, differentiation, invasiveness, and tumor progression in several cancers. We wanted to examine the possible impact of single nucleotide polymorphisms (SNPs)… read more here.

Keywords: risk; edn1; papillary thyroid; snp ... See more keywords
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The EDN1 Missense Variant rs5370G > T Regulates Adaptation and Maladaptation under Hypobaric Hypoxia

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Published in 2022 at "International Journal of Environmental Research and Public Health"

DOI: 10.3390/ijerph191811174

Abstract: Endothelin 1 (EDN1) encodes a potent endogenous vasoconstrictor, ET1, to maintain vascular homeostasis and redistribution of tissue blood flow during exercise. One of the EDN1 missense polymorphisms, rs5370 G/T, has strongly been associated with cardiopulmonary… read more here.

Keywords: edn1; physiology; adaptation maladaptation; edn1 missense ... See more keywords