Inhibition of polycomb repressive complex 2 by targeting EED protects against cisplatin‐induced acute kidney injury
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DOI: 10.1111/jcmm.17447
Abstract: Polycomb repressive complex 2 (PRC2) is a multicomponent complex with methyltransferase activity that catalyzes trimethylation of histone H3 at lysine 27 (H3K27me3). Interaction of the epigenetic reader protein EED with EZH2, a catalytic unit of… read more here.
Keywords: repressive complex; acute kidney; kidney; polycomb repressive ... See more keywords