A Bioactive Benzimidazole-Cyclometalated Iridium(III) Complex as an Epigenetic Regulator through Effectively Interrupting the EED-EZH2 Interaction.
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DOI: 10.1002/smll.202405771
Abstract: Epigenetic regulation plays a fundamental role in controlling gene expression and maintaining cellular identity. Among epigenetic processes, the translocation of methyltransferases is critical for the modification of chromatin structure and transcriptional activity. The regulation of… read more here.
Keywords: bioactive benzimidazole; iii complex; eed ezh2; interaction ... See more keywords