Design, Synthesis, and Molecular Modeling Studies of Novel Coumarin Carboxamide Derivatives as eEF-2K Inhibitors
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DOI: 10.1021/acs.jcim.9b01083
Abstract: Eukaryotic elongation factor-2 kinase (eEF-2K) is an unusual alpha kinase and commonly upregulated in various human cancers, including breast, pancreatic, lung and brain tumors. We have demonstrated that eEF-2K is relevant to poor prognosis and… read more here.
Keywords: design synthesis; molecular modeling; novel coumarin; breast ... See more keywords