eEF1A1 promotes colorectal cancer progression and predicts poor prognosis of patients
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DOI: 10.1002/cam4.4848
Abstract: Colorectal cancer (CRC) is a major leading cause of cancer mortality worldwide in which dysregulated protein synthesis plays an etiologic role. The eukaryotic elongation factor 1 A1 (eEF1A1) exerts significant effects on protein synthesis by… read more here.
Keywords: eef1a1; poor prognosis; crc; colorectal cancer ... See more keywords
Pediatric lipoblastoma with a novel EEF1A1‐PLAG1 fusion
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DOI: 10.1002/gcc.22945
Abstract: To the Editor: We read with interest the recent study by Chung et al reporting three distinctive myxoid-fibroblastic soft tissue tumors in children characterized by two unusual PLAG-1 fusions, involving YWHAZ and EEF1A genes as… read more here.
Keywords: plag1 fusion; eef1a1; lipoblastoma; plag1 ... See more keywords
Dynamic regulation of eEF1A1 acetylation affects colorectal carcinogenesis
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DOI: 10.1515/hsz-2022-0180
Abstract: Abstract The dysregulation of the translation elongation factor families which are responsible for reprogramming of mRNA translation has been shown to contribute to tumor progression. Here, we report that the acetylation of eukaryotic Elongation Factor… read more here.
Keywords: eef1a1 k439; acetylation; eef1a1; colorectal carcinogenesis ... See more keywords
High eEF1A1 Protein Levels Mark Aggressive Prostate Cancers and the In Vitro Targeting of eEF1A1 Reveals the eEF1A1–actin Complex as a New Potential Target for Therapy
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DOI: 10.3390/ijms23084143
Abstract: Although the eukaryotic elongation factor eEF1A1 plays a role in various tumours, there is little information on its prognosis/therapeutic value in prostate carcinoma. In high-grade and castration-resistant prostate carcinoma (CRPC), the identification of novel therapeutic… read more here.
Keywords: prostate; eef1a1; protein levels; cancer ... See more keywords