Synergistic Effect of Amyloid-β and Tau Disrupts Neural Circuits.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00037
Abstract: Alzheimer's disease (AD) is characterized by the coexistence of amyloid-β (Aβ) plaques and tau-based neurofibrillary tangles. Although studies have shown that the interaction between Aβ and tau causes enhanced AD pathology; there is a lack… read more here.
Keywords: amyloid tau; tau; effect amyloid; neural circuits ... See more keywords
Anionic lipids modulate little the reorganization effect of amyloid-beta peptides on membranes.
Sign Up to like & getrecommendations! Published in 2023 at "General physiology and biophysics"
DOI: 10.4149/gpb_2022052
Abstract: Amyloid-β peptide interactions with model lipid membranes have been studied by means of small angle neutron scattering and molecular dynamics simulations. These interactions had been indicated recently as an origin of the membrane structure reorganizations… read more here.
Keywords: little reorganization; lipids modulate; anionic lipids; reorganization effect ... See more keywords