The Allosteric Effect in Antibody-Antigen Recognition.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1154-8_11
Abstract: We studied the molecular details of the recognition of antigens by the variable domain of their cognate antibodies in as well as those elicited by the constant domains, which do not directly interact with antigens.… read more here.
Keywords: effect antibody; allosteric effect; antigen recognition; recognition ... See more keywords
Bystander effect of antibody–drug conjugates: fact or fiction?
Sign Up to like & getrecommendations! Published in 2022 at "Current Oncology Reports"
DOI: 10.1007/s11912-022-01266-4
Abstract: Summarizing the current preclinical and clinical evidence about bystander effect of antibody–drug conjugates (ADCs) in solid tumors. One of the main challenges of treating solid tumors with ADCs is the heterogeneous expression of the target… read more here.
Keywords: drug conjugates; bystander; effect antibody; antibody drug ... See more keywords