Mechanistic insights on the effect of crocin, an active ingredient of saffron, on atherosclerosis in apolipoprotein E knockout mice
Sign Up to like & getrecommendations! Published in 2022 at "Coronary Artery Disease"
DOI: 10.1097/mca.0000000000001142
Abstract: Background We investigated the effect of crocin treatment on atherosclerosis and serum lipids in apolipoprotein E knockout (ApoE−/−) mice, focusing on the expression of endothelial nitric oxide synthase (eNOS) and hypoxia-induced factor-1 alpha (HIF-1α). Methods… read more here.
Keywords: effect crocin; apolipoprotein knockout; expression; crocin ... See more keywords
Inhibitory Effect of Crocin Against Gastric Carcinoma via Regulating TPM4 Gene
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DOI: 10.2147/ott.s254167
Abstract: Background Gastric cancer (GC) is one of the most common malignant tumors and the second most frequent cause of cancer death worldwide. Crocin is a kind of bioactive constituent found in the stigmas of saffron,… read more here.
Keywords: inhibitory effect; crocin; gene; effect crocin ... See more keywords
Protective effect of crocin on hemodynamic parameters, electrocardiogram parameters, and oxidative stress in isolated hearts of rats exposed to PM10
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.61163.13533
Abstract: Objective(s): Exposures to particulate matter (PM) have been related to increased risk for cardiovascular health effects and can promote cardiac ischemia and oxidative stress. Crocin has strong antioxidant properties and stress-reducing effects. Therefore, this study… read more here.
Keywords: effect crocin; rats exposed; oxidative stress; crocin ... See more keywords
The effect of Crocin on sperm parameters disorders induced by peripheral administration of nitrosamines in male rats
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DOI: 10.25122/jml-2019-0144
Abstract: Nitrosamines are carcinogenic agents which can unfavorably affect some male reproductive parameters. Humans are exposed to nitrosamines through various routes, the most important of which is the diet. Crocin is a carotenoid and is accountable… read more here.
Keywords: sperm parameters; male rats; effect crocin; crocin nitrosamine ... See more keywords
The Functional Vision Restorative Effect of Crocin via the BDNF–TrkB Pathway: An In Vivo Study
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DOI: 10.3390/nu14091716
Abstract: Abnormal dislocation of cone opsin protein affects the sensitivity function of photoreceptors and results in depressed central vision. Nutraceutical therapy is needed to restore the residual function of photoreceptors. Crocin is a natural substance for… read more here.
Keywords: functional vision; effect crocin; restorative effect; vision ... See more keywords