The effect of dihydroceramide desaturase 1 inhibition on endothelial impairment induced by indoxyl sulfate.
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DOI: 10.1016/j.vph.2021.106923
Abstract: Protein-bound uremic toxins (PBUTs) have adverse effects on vascular function, which is imperative in the progression of cardiovascular and renal diseases. The role of sphingolipids in PBUT-mediated vasculo-endothelial pathophysiology is unclear. This study assessed the… read more here.
Keywords: inhibition; effect dihydroceramide; indoxyl sulfate; dihydroceramide desaturase ... See more keywords