A New Molecular Mechanism Underlying the Antitumor Effect of DNA Methylation Inhibitors via an Antiviral Immune Response.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in protein chemistry and structural biology"
DOI: 10.1016/bs.apcsb.2016.08.005
Abstract: Chromatin remodeling mediated by DNA methylation and histone modifications play critical roles in the transcriptional regulation of protein-coding genes, noncoding RNAs such as microRNAs, and endogenous retroviruses (ERVs). Many studies have shown that aberrant DNA… read more here.
Keywords: effect dna; methylation; dna methylation; methylation inhibitors ... See more keywords
Effect of DNA aptamer through blocking of negative regulation of Wnt/β‐catenin signaling in human hair follicle dermal papilla cells
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DOI: 10.1111/srt.13326
Abstract: When Wnt binds to the N‐terminal of Frizzled, a conformational change occurs in the C‐terminal of Frizzled, which binds to Dishevelled1 (Dvl1), a Wnt signaling component protein. When Dvl1 binds to the C‐terminal of Frizzled,… read more here.
Keywords: dna aptamer; aptamer blocking; terminal frizzled; effect dna ... See more keywords
Manganese-based nanoadjuvants for enhancement of immune effect of DNA vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1053872
Abstract: As a highly pathogenic avian influenza virus, influenza A (H5N1) has been reported to infect humans, posing a major threat to both poultry industry and public health. It is an urgent need to develop a… read more here.
Keywords: dna; dna vaccines; immune effect; effect dna ... See more keywords