Letter to the Editor: Patient‐Reported Outcomes for Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis: Rationale for Expanded Use
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30356
Abstract: 443 placebo is observed in patient-reported outcomes or subjective measures; the effect of placebo on objective biomarkers or hard outcomes such as mortality are likely minimal.(2) Hence, in this study, when evaluating mortality as primary… read more here.
Keywords: reported outcomes; indirect comparisons; effect; effect estimates ... See more keywords
Abbreviated and comprehensive literature searches led to identical or very similar effect estimates: meta-epidemiological study.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of clinical epidemiology"
DOI: 10.1016/j.jclinepi.2020.08.002
Abstract: OBJECTIVE Assessing the agreement of treatment effect estimates from meta-analyses based on abbreviated or comprehensive literature searches. STUDY DESIGN AND SETTING Meta-epidemiological study. We abbreviated 47 comprehensive Cochrane review searches and searched MEDLINE/Embase/CENTRAL alone, in… read more here.
Keywords: abbreviated comprehensive; led identical; effect; literature searches ... See more keywords
Risk of Bias and Its Impact on Intervention Effect Estimates of Randomized Controlled Trials in Endodontics.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of endodontics"
DOI: 10.1016/j.joen.2019.10.016
Abstract: INTRODUCTION The aims of this study were to evaluate the methodological quality of randomized controlled trials (RCTs) recently published in endodontics and to investigate the influences of methodological characteristics on the magnitude of treatment effects.… read more here.
Keywords: controlled trials; effect estimates; intervention effect; randomized controlled ... See more keywords
Comparison of closure versus non-closure of the intraoral buccal mucosa graft site in urethroplasties. A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2022 at "Arab Journal of Urology"
DOI: 10.1080/2090598x.2022.2097613
Abstract: ABSTRACT Aim To assess postoperative oral morbidity through meta-analysis of comparative studies for closure or non-closure of the buccal mucosa graft harvest area in patients undergoing urethroplasty. Methods A systematic literature review was conducted in… read more here.
Keywords: time; meta analysis; effect estimates; closure ... See more keywords
Association Between Lack of Blinding and Mortality Results in Critical Care Randomized Controlled Trials: A Meta-Epidemiological Study*
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DOI: 10.1097/ccm.0000000000005065
Abstract: Supplemental Digital Content is available in the text. OBJECTIVES: To investigate whether intervention effect estimates for mortality differ between blinded and nonblinded randomized controlled trials conducted in critical care. We used a meta-epidemiological approach, comparing… read more here.
Keywords: critical care; effect estimates; controlled trials; randomized controlled ... See more keywords
Conditions for Generating Treatment Effect Estimates in Line With Objectives: Beyond Confounding.
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DOI: 10.1097/mlr.0000000000000614
Abstract: D iscussions around the validity of treatment effect estimates in comparative effectiveness research (CER) commonly focus on general concepts of bias and, specifically, whether assumptions related to confounding are satisfied. Although necessary, confounding is only… read more here.
Keywords: average treatment; treatment; cer; effect estimates ... See more keywords
Variation of effect estimates in the analysis of mortality and length of hospital stay in patients with infections caused by bacteria-producing extended-spectrum beta-lactamases: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "BMJ Open"
DOI: 10.1136/bmjopen-2019-030266
Abstract: Objective To assess the variation of effect estimates in the analysis of mortality and length of stay (LOS) in patients with infections caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae. Design Systematic review and meta-analysis Methods Literature… read more here.
Keywords: analysis; effect estimates; meta analysis; mortality ... See more keywords
Key concepts for informed health choices. 2.4: descriptions of effects should reflect the risk of being misled by the play of chance
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Royal Society of Medicine"
DOI: 10.1177/01410768221140750
Abstract: When there are few outcome events, differences in outcome frequencies between the treatment comparison groups may easily have occurred by chance and may mistakenly be attributed to differences in the effects of the treatments, or… read more here.
Keywords: effect estimates; small studies; effect; risk ... See more keywords
Comparison of statistical methods used to meta-analyse results from interrupted time series studies: an empirical study
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DOI: 10.1186/s12874-024-02147-z
Abstract: Background The Interrupted Time Series (ITS) is a robust design for evaluating public health and policy interventions or exposures when randomisation may be infeasible. Several statistical methods are available for the analysis and meta-analysis of… read more here.
Keywords: meta analysis; analysis; meta analytic; effect estimates ... See more keywords
Application of the Composite Quality Score (CQS-2B) versus Cochrane’s Risk of Bias tool (Version 2) in systematic reviews of clinical trials – an exploratory study
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2024.1307815
Abstract: Objectives To explore whether systematic review conclusions generated from Cochrane’s second version of its Risk of Bias tool (RoB 2) for trial appraisal differ when the Composite Quality Score, Version 2.B (CQS-2B) is used instead… read more here.
Keywords: tool; risk; effect estimates; bias ... See more keywords